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Selecting the Correct Septa

It's vital to choose the right septa for your application. The wrong septa can compromise the accuracy of your results and reduce the lifespan of your supplies (increasing overall costs).

The below chart shows some common septa materials along with their compatibilities, incompatibilities, and resealability.

However, please don't accept the below data as final! Real-world results depend on a complex array of factors, including the specifics of your application and the quality of the material. If in doubt, it's recommended that you your own testing with different septa materials to determine the perfect match for your application.

Septa Material Compatible Incompatible Resealability
Butyl Rubber Acetone, alcohols, diethylamine, DMSO, MEK, sodium peroxide Benzene, chloroform, DMF, HF, HCL, phenol, toluene, xylene Very good
Butyl Rubber / PTFE PTFE resistance until punctured, then septa or liner will have compatibility of butyl rubber PTFE does not reseal after being punctured
PTFE Diethylamine, fluorine Single injection use
Red Rubber Acetone, alcohols, diethylamine, DMSO, sodium peroxide Chloroform, DMF, HF, HCL, MEK, phenol, toluene, xylene Excellent
Red Rubber / PTFE PTFE resistance until punctured, then septa or liner will have compatibility of red rubber PTFE does not reseal after being punctured
Silicone Alcohol, DMF, DMSO, hydrogen peroxide, sodium hydroxide ACN, benzene, chloroform, hexane, HCL, MEK, THF, toluene
Silicone / PTFE PTFE chemical resistance until punctured, then septa or liner will have compatibility of silicone PTFE does not reseal after being punctured
Viton® Alcohols, benzene, chlorinated solvents, HF, heptane, hexane Acetone, ACN, DMF, dioxane, pyridine, ketones, MEK, THF Good

The above data is provided courtesy of Ace Glass, Inc.